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- Pfe article review in 2021
- Fda reviews pfizer
- Pfe fda approval
- Pfe vaccine
- Fda set to approve covid vaccine
- Pfe fda approval date
- Estimated fda approval for covid vaccine
- Pfizer vaccine reviews
Pfe article review in 2021
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Fda reviews pfizer
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Pfe fda approval
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Pfe vaccine
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Fda set to approve covid vaccine
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Pfe fda approval date
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Estimated fda approval for covid vaccine
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Pfizer vaccine reviews
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What does primary failure of eruption ( PFE ) mean?
Background: Primary failure of eruption (PFE) is a rare disease defined as incomplete tooth eruption despite the presence of a clear eruption pathway. Orthodontic extrusion is not feasible in this case because it results in ankylosis of teeth.
What does PFE stand for in dental terms?
PFE involves partial or complete non-eruption of initially non-ankylosed teeth due to a disturbed eruption mechanism, resulting in a posterior unilateral/bilateral open bite. Orthodontic extrusion is not feasible because this procedure will cause the teeth to become ankylosed.
Can a primary tooth be affected by PFE?
Infraocclusion of the posterior teeth, especially if both sides are affected, is the hallmark of PFE. If a patient is affected by PFE, all teeth distal to the most mesial tooth are also affected by PFE. Primary teeth can also be impacted; however, this may not necessarily occur. If a patient is susp …
What should I do if I think I have PFE?
If a patient is suspected of having PFE, a genetic test for mutation in the PTH1R gene should be recommended prior to any orthodontic treatment to avoid ankylosis. Treatment options depend on the patient's age and the clinical situation, and they must be evaluated individually.
Last Update: Oct 2021
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